Bupropion Aplenzin generic Zyban is prescribed for depression and smoking cessation. It increases the levels of certain chemicals in the brain and reduces the cravings, anxiety, irritability and other symptoms associated with depression. More Info about Bupropion. Oral- Smoking cessation- Adult: Modified-release preparation: Initially, mg once daily for 6 days then increased to mg twice a day.
Period of treatment: wk. Depression Adult: Initially, mg twice a day increased to mg three times a day after 3 days if necessary. Increase further to mg twice a day if no improvement has been observed after several week of therapy. It comes as a tablet and a sustained-release or extended-release long-acting tablet to take by mouth, without meals. Contraindicated in patients who are allergic to bupropion, history of convulsions, eating disorders, with MAO inhibitors or those who are planning to stop sedatives or alcohol suddenly.
They may increase the risk of seizures. Zyban bupropion hydrochloride is a prescription medicine that does not have nicotine and helps people quit smoking. For many people, it cuts down on cravings and withdrawal symptoms such as irritability, frustration or anger, anxiety, trouble concentrating, restlessness and depression.
Zyban works with the chemicals in the brain dopamine and norepinephrine that are associated with nicotine addiction, cravings and withdrawal symptoms. You should not take Zyban if you:. It is best not to drink alcohol while taking Zyban.
If you drink alcohol and suddenly stop, you may increase your chance of having a seizure. It is very important to talk about this with your doctor. Measure ad performance. Select basic ads. Create a personalised ads profile. Select personalised ads. Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. Zyban is the brand name for the generic drug bupropion hydrochloride. It is a nicotine-free quit aid.
Originally marketed as an anti-depressant drug under the brand name of Wellbutrin, it became apparent that bupropion was an effective quit aid because smokers using it to treat depression also lost interest in smoking. People not planning to quit smoking found themselves stopping with relative ease. Later, bupropion hydrochloride was given the brand name of Zyban and in , the FDA approved it as a quit smoking aid.
When used in combination with nicotine replacement therapy NRTs , the chance for long-term success with smoking cessation increases. Note: it is important to be monitored by your doctor if you're using both Zyban and an NRT as high blood pressure can be a concern. It isn't completely understood how Zyban works, but we do know that it alters brain chemistry in such a way that nicotine is rendered less effective.
While this medication was developed as an anti-depressant, you do not need to suffer from depression for it to work as a quit aid. That said, if you develop quit-related depression, Zyban may help to offset the symptoms.
Zyban is not sold over the counter, so you must see your doctor for a prescription. To begin with, you take Zyban while you're still smoking. Days 1 - 3: One mg tablet once a day. Days 4 - 7: One mg tablet twice a day, at least 8 hours apart. Decreased kidney function can cause this medication to build up in the body, causing side effects. If you have kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: Bupropion is removed from the body by the liver. Decreased liver function can cause this medication to build up in the body, causing side effects. If you have liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
This medication may also cause a decrease in liver function. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Mental health: Bupropion may cause behavior and thought disturbances to worsen for people who have psychotic conditions. It may also cause symptoms of psychosis and mania to develop for people who have not had these symptoms before. If you experience symptoms such as hallucinations, mania feeling unusually over-excited or uninhibited , or delusional thinking, or notice them in a family member who is taking this medication, contact your doctor as soon as possible.
Seizure risk: This medication may increase the risk of seizures. If you are at risk of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Serotonin syndrome: Severe reactions are possible when bupropion is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors — other medications used to treat depression.
Similar effects occur when too much bupropion is taken or is allowed to build up in the body. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, and changes in mental state including delirium and agitation. These reactions should be treated as a medical emergency and immediate medical treatment should be obtained as coma and death are possible.
Suicidal or agitated behaviour, or other behaviour changes: Adults and children taking this medication may feel agitated restless, anxious, aggressive, emotional, and feeling not like themselves , or they may want to hurt themselves or others. These symptoms may occur within several weeks after people start taking this medication. If you experience these side effects or notice them in a family member who is taking this medication, contact your doctor immediately. Your doctor will monitor you for emotional and behavioural changes while you are taking bupropion.
Pregnancy: The safety of bupropion during pregnancy has not been established. It has been reported that babies born to pregnant women who have taken medications of this kind during the last trimester of pregnancy may be adversely affected. Physicians and pregnant women should carefully consider the benefits and the risks of all treatment options.
If you become pregnant while taking this medication, contact your doctor immediately. Breast-feeding: Bupropion passes into breast milk. Because this medication presents risks to breast-feeding infants, a decision should be made whether to discontinue breast-feeding or to discontinue bupropion, taking into account the importance of the medication to the mother.
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