If they stand up too quickly after administering the dose, their blood pressure may drop even lower and put them at risk of fainting. The most common side effect of long-acting nitroglycerin is a headache, but this side effect decreases with medication use.
Although people only apply rectal ointment to the anus, they may still experience headaches and dizziness. Some people may have allergies to nitroglycerin, so doctors do not recommend that people use it if they have a history of allergic reactions to this medication.
Doctors do not prescribe nitroglycerin to anyone with a history of severe anemia , heart attack occurring on the right side of the heart, or increased pressure in the brain.
Nitroglycerin contraindications include allergic reactions, though these reactions are rare. Other contraindications include:. Nitroglycerin may interact with certain other medications, such as PDE-5 inhibitors.
PDE-5 inhibitors are drugs that doctors give to treat erectile dysfunction. As with nitroglycerin, these drugs also cause increased blood flow and can lower blood pressure. Doctors do not recommend that people use nitroglycerin with PDE-5 inhibitors, as these medications can cause fainting if someone is taking them together. People should avoid using nitroglycerin if they have taken Viagra or Levitra within the past 24 hours or Cialis within the past 48 hours.
The nitroglycerin dosage may be different for different people. For example, the dosage may depend on the form of the drug a person is using. It can also change based on:.
Generic nitroglycerin comes in the form of a sublingual tablet. The strengths of these tablets are 0. Brand-name nitroglycerin, Nitrostat, comes in the form of a sublingual tablet. The strengths of this tablet are 0. An overdose of nitroglycerin may occur when a person uses PDE-5 inhibitors with nitroglycerin or uses too much nitroglycerin during an angina attack. Currently, no drug can reverse a nitroglycerin overdose.
That said, doctors can provide care to people experiencing an overdose by giving them intravenous fluids and elevating their legs. Using nitroglycerin in the appropriate way can delay the serious complications of angina, which include heart attack, stroke , and even death. People may experience side effects with nitroglycerin, so they should remain seated while the drug takes effect. Nitroglycerin can interact with erectile dysfunction medications. People with angina should report the use of Viagra, Cialis, and Levitra to a doctor because using both drugs together may be dangerous.
People can also treat anal fissures using nitroglycerin rectal ointment. Side effects and interactions can also occur with the topical use of nitroglycerin. Angina is pain, squeezing, or pressure in the chest. It signals that too little oxygen is reaching the heart. Learn more here, including when to seek….
The coronary arteries supply oxygen and blood to the heart. Learn more about coronary artery disease causes, symptoms, risk factors, and more. Pain in the chest may cause people to worry. Although some causes are severe, such as heart attacks, many of the potential causes are less worrisome…. Stable angina causes pain, squeezing, or tightness in the chest, usually when someone is stressed or doing physical activity. Narrowed arteries or…. Here, learn to recognize a heart attack and what to do next.
We also describe treatment and recovery and provide tips for prevention. This medicine may cause headaches. These headaches are a sign that the medicine is working. Do not stop using the medicine or change the time you use it in order to avoid the headaches. Ask you doctor if you can take aspirin or acetaminophen to treat the headache.
Dizziness, lightheadedness, or faintness may occur, especially when you get up quickly from a lying or sitting position. Getting up slowly may help. Dizziness, lightheadedness, or fainting is also more likely to occur if you drink alcohol, stand for long periods of time, exercise, or if the weather is hot.
While you are using this medicine, be careful to limit the amount of alcohol you drink. Also, use extra care during exercise or hot weather or if you must stand for long periods of time. Do not stop using this medicine without checking with your doctor first. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. Tell the doctor in charge that you are using this medicine before having a magnetic resonance imaging MRI scan.
Skin burns may occur at the site where the patch is worn during this procedure. Ask your doctor if the patch should be removed before having an MRI scan. You might need to put on a new patch after the procedure. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention.
These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Other side effects not listed may also occur in some patients.
If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
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Advertising Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Nitroglycerin ointment can only be used to prevent attacks of angina; it cannot be used to treat an attack of angina once it has begun.
Nitroglycerin ointment Rectiv is used in adults to treat pain from anal fissures a split or tear in the tissue near the rectal area. Nitroglycerin is in a class of medications called vasodilators. Nitroglycerin ointment prevents angina by relaxing the blood vessels so that the heart does not need to work as hard and therefore does not need as much oxygen. Nitroglycerin ointment treats anal fissure pain by relaxing the blood vessels, which reduces the pressure in the anal tissues.
Topical nitroglycerin comes as an ointment to apply to the skin. When used to prevent angina, it is usually applied twice a day, once right after waking in the morning, and again 6 hours later. When used to treat anal fissure pain, it is usually applied every 12 hours for up to 3 weeks. If you still have anal fissure pain after using the ointment for 3 weeks, call your doctor.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use nitroglycerin ointment exactly as directed. Do not apply more or less of it or apply it more often than prescribed by your doctor.
If you are using nitroglycerin ointment to prevent angina, your doctor will probably start you on a lower dose of nitroglycerin ointment and may gradually increase your dose as needed to control your angina. Nitroglycerin ointment may not work as well after it has been used for some time, especially at higher doses.
To help prevent this, your doctor will schedule your doses so that there is a period of time when you are not exposed to nitroglycerin every day. If your angina attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Nitroglycerin ointment helps to prevent angina attacks but does not cure coronary artery disease.
Continue to use nitroglycerin ointment even if you feel well. Do not stop using nitroglycerin ointment without talking to your doctor. If you are using nitroglycerin ointment to prevent angina, follow your doctor's directions and the guidelines in this paragraph to apply the medication. Nitroglycerin ointment comes with a paper applicator with a ruled line for measuring the dose in inches. Place the paper on a flat surface and squeeze the ointment onto the paper, carefully measuring the amount specified on your prescription label.
If your ointment comes in foil packets, you should know that each packet contains 1 inch of ointment and is to be used for a single dose only. Place the paper on your skin with the ointment side down, and use the paper to lightly spread the ointment to cover an area of skin at least as large as the applicator.
Do not rub the ointment into the skin. Tape the applicator in place and cover it with a piece of plastic kitchen wrap to prevent the ointment from staining your clothing.
If your ointment comes in a tube, replace the cap and screw it on tightly. If your ointment came in a small foil packet, dispose of the packet. Try not to get the ointment on your fingers. Wash your hands after applying the ointment. If you are using nitroglycerin ointment to treat anal fissure pain, follow your doctor's directions and the guidelines in this paragraph to apply the medication.
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