This skin check will allow for a proper diagnosis and treatment plan. Save my name, email, and website in this browser for the next time I comment. The truth about Black Salve. Previous Next. View Larger Image. So what should you know about Black Salve? What is Black Salve?
Is there any evidence that Black Salve cures cancer? Is Black Salve dangerous? About the Author: Helena Rosengren. Skin Repair's chief doctor Helena Rosengren is also a senior lecturer at James Cook University, has published several papers in medical journals and runs skin cancer workshops for GPs all over Australia!
Dr Rosengren is also a fellow of the Australasian College of Skin Cancer Medicine, and undertakes complex surgery with meticulous attention to cosmetic results. The other major ingredient Sanguinaria canadensis is a perennial flowering plant native to North Eastern America and the ingredient is known colloquially as bloodroot, Indian Paint and redroot [ 2 ].
When the root is harvested and cut, a red liquid drains which thickens to a paste. This paste is also a strong escharotic and has been used by indigenous Americans to treat warts, polyps and moles [ 2 ].
The active ingredient in the bloodroot rhizome is a benzyl isoquinolone alkaloid [BIA]. Sanguinarine contains antimicrobial properties [ 5 ], and invitro studies show that it also contains potent anti-cancer properties [ 6 ]. A recently published research article has shown that sanguinariine is a rapid inducer of melanoma caspase-dependent cell death that is mediated by oxidative stress [ 7 ].
Despite arguable molecular rationale for the topical application of these natural compounds, preclinical and clinical data in this field are still scant and no controlled clinical trial has yet been published demonstrating any relevant clinical efficacy. Many testimonials praising the results of Cansema are also listed on the Internet [ 9 ].
It is likely that some patients researching cancer treatments on the Internet might not be aware that testimonials are not valid scientific proof.
The case presented here involves a patient who, having had an initial diagnosis of thin invasive melanoma, decided to follow the option of an alternative cancer treatment rather than conventional evidence based treatment. The reason the patient gave for seeking alternative treatment in was the cost of immediate surgical management in the Australian private health system.
When she failed to attend this private appointment, her GP contacted her. The GP then arranged for her to be seen in the local public hospital at no cost, though there was going to be a delay of a couple of weeks for the appointment.
Once again the patient did not attend this appointment. At that time the patient was reportedly also encouraged by an acquaintance to use black salve. It is speculation, but perhaps having witnessed the death of her brother at age 80 and her own son at age 23 from cerebral metastatic melanoma, the patient was in denial of her own disease.
As it turned out, there was a time delay of seven years before she agreed to conventional management of her melanoma. During this time there were consultations with three GPs, three surgeons, one dermatologist, one radiologist and an oncologist. The patient exercised the undisputed right to follow the treatment regimen of personal choice. Over a period of seven years the disease progressed both locally and systemically.
It is not known whether distant metastases were already present at the time of original diagnosis, but based on the staging of the tumor Stage 1 , the prognosis for year disease-free survival was Ten-year survival prognosis for Stage 4 melanoma lung metastases is 2. We believe it is essential that patients are adequately informed about evidence-based treatment and warned about the potential adverse consequences associated with an alternative treatment regimen but we also believe that support should continue to be provided regardless of choices made.
Funding: None. National Center for Biotechnology Information , U. Journal List Dermatol Pract Concept v. Dermatol Pract Concept. Published online Jul Graham W. Sivyer 1 and Cliff Rosendahl 1. Author information Article notes Copyright and License information Disclaimer. Competing interests: The authors have no conflicts of interest to disclose.
Received Nov 25; Accepted Dec This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The TGA is advising consumers against purchasing or using black salve, red salve or cansema products. The TGA is not aware of any credible, scientific evidence that black salve, red salve or cansema can cure or treat cancer. In addition there is no evidence that these products can be used to diagnose cancers.
In fact, the evidence shows that they will cause skin irritation regardless of whether any malignancy is present. While some Internet sites contain testimonials supporting the use of these products, the TGA does not consider this to be adequate evidence to support their efficacy. If you have used any black salve, red salve or cansema products and you are concerned about a possible adverse reaction, speak to a health professional. Consumers and health professionals should report any adverse reactions associated with the use of any of these products to the TGA.
As at June , the TGA has received four notifications of adverse events involving the use of products described as black salve, red salve or cansema. Each of these reports describes damage to the skin, subcutaneous tissue and, in one case, muscle following the application of these products. Three of the reported cases required medical intervention or follow up and in two of the cases significant scarring resulted.
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